From the same as aiteo; a cause (as if asked for), i.e. (logical) reason (motive, matter), (legal) crime (alleged or proved) -- accusation, case, cause, crime, fault, (wh-)ere(-fore).
see GREEK aiteo
1. cause, reason: Acts 10:21; Acts 22:24; Acts 28:20; κατά πᾶσαν αἰτίαν for every cause, Matthew 19:3; δἰ ἥν αἰτίαν for which cause, wherefore, Luke 8:47; 2 Timothy 1:6, 12; Titus 1:13; Hebrews 2:11; cf. Grimm on 2 Macc. 4:28.
2. cause for which one is worthy of punishment; crime of which one is accused: Matthew 27:37; Mark 15:26; John 18:38; John 19:4 (6; Acts 23:28); αἰτία θανάτου (A. V. cause of death) crime deserving the punishment of death, Acts 13:28; Acts 28:18.
3. charge of crime, accusation: Acts 25:18, 27. (All these meanings are in secular writings also; (but Liddell and Scott now make meaning 3 the primary one).) In Matthew 19:10 the words εἰ οὕτως ἐστιν ἡ αἰτία τοῦ ἀνθρώπου μετά τήν γυναικός find a simple explanation in a Latinism (causa equivalent tores:si ita res se habet, etc.) if the case of the man with his wife is so.